5α Alpha Reductase Hair Loss

5α Alpha Reductase Hair Loss - In young men and men of middle age in 95% hair thinning is associated with genetics. Alopecia in men can be transmitted by inheritance  (androgenetic alopecia). Androgenetic hair loss is associated with an increase in hormones - androgens, which turn the male gender hormone testosterone into dihydrotestosterone.  Dihydrotestosterone (DHT)  - a biologically active form of testosterone, formed from it in the cells of target organs under the action of the enzyme 5α-reductase. 

Activity blockers 5 alpha rare cytosine - 5α represent substances that block the androgen receptors of the hair follicle, thereby reducing its sensitivity to the hormone dihydrotetosterone (DHT).

As a result, a barrier is created around the hair follicle, which does not pass the hormone dihydrotetosterone. As a consequence, the hair does not interfere with growth, pass through all phases of the life cycle of hair growth .

However, using only the blockers of the activity of 5 alpha reductase (5α) will not give a particularly visible result.

We said that the hair follicle is damaged by exposure to the hormone dihydrotetosterone. The action of 5 alpha reductase inhibitors is aimed at reducing the sensitivity of androgen receptors of hair follicles to the hormone dihydrotestosterone.
5α Alpha Reductase Hair Loss
Often, patients who use only 5 AC blockers , note a very short-term effect with the following possible options:

After the end of another, as a rule, 3-month course, hair falls off for 3 weeks.

There is a stopping of the process of hair loss, but on its background the growth of thick and healthy hair is not observed.

Why is this happening? We also said that under the influence of dihydrotestosterone, the hair follicle is depressed, if nothing is done, gradually atrophies, i.e. speaking in simple language "falls ill."

When the 5 alpha alfa reductase blockers are taken , a temporary barrier is created, the follicle becomes temporarily "easier to breathe" and against the background of this growth of thinned hair is noted. Such an imaginary result. After the course of treatment, the protection of the follicle eventually goes away, but the hair follicle remains damaged, how can it produce full-fledged hair? The process of "suppressing the hair follicles" went further, the result - the resumption of hair loss, the rapid disappearance of the imaginary effect.

Therefore, use only drugs - blockers of 5 alpha reductase activity, in the treatment of androgenic alopecia and diffuse hair loss is not advisable.

Blockers of 5 alpha reductase are used together with proteins and vitamin-nutrient complexes, stimulating regenerative and health-improving processes in the hair follicles.